GPCR Phosphorylation in Biased Agonism 1 Modulating μ-Opioid Receptor Phosphorylation Switches Agonist-Dependent Signaling as Reflected in PKCε Activation and Dendritic Spine Stability
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چکیده
1 Modulating μ-Opioid Receptor Phosphorylation Switches Agonist-Dependent Signaling as Reflected in PKCε Activation and Dendritic Spine Stability Hui Zheng, Ji Chu, Yuhan Zhang, Horace H. Loh and Ping-Yee Law From Department of Pharmacology, University of Minnesota, 6-120 Jackson Hall, 321 Church St. S.E., Minneapolis, Minnesota, 55455-0217, USA. South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 190 Kaiyuan Road, Guangzhou, 510530, China. Running Head: GPCR Phosphorylation in Biased Agonism Address correspondence to: Hui Zheng, 6-120 Jackson Hall, 321 Church St. S. E., Minneapolis, MN 55455-0217, Tel: 6126266539; Fax: 6126258408; E-mail: [email protected]
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